Diagnosis of mediastinal mycobacterial lymphadenopathy by transbronchial needle aspiration

Chest. 1991 Dec;100(6):1723-4. doi: 10.1378/chest.100.6.1723.


A 35-year-old man with the acquired immunodeficiency syndrome (AIDS) presented with a multitude of constitutional symptoms, fever, and marked intrathoracic lymphadenopathy. Results of initial diagnostic examination were unrevealing, and bronchoscopy with fine-gauge flexible transbronchial needle aspiration (TBNA) of subcarinal lymph nodes was performed. Two aspirates were obtained, one for cytologic study and the other for acid-fast smear. Despite obtaining acid-fast smears from numerous sites, only TBNA provided evidence of acid-fast organisms and prompted early antimycobacterial therapy. We believe this is the first report of mycobacterial intrathoracic lymphadenopathy diagnosed by TBNA.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Biopsy, Needle*
  • Humans
  • Lymphatic Diseases / complications
  • Lymphatic Diseases / diagnosis*
  • Lymphatic Diseases / diagnostic imaging
  • Male
  • Mediastinal Diseases / complications
  • Mediastinal Diseases / diagnosis*
  • Mediastinal Diseases / diagnostic imaging
  • Mycobacterium avium-intracellulare Infection / complications
  • Mycobacterium avium-intracellulare Infection / diagnosis*
  • Radiography