Characteristics of 400-meter walk test performance and subsequent mortality in older adults

Rejuvenation Res. 2009 Jun;12(3):177-84. doi: 10.1089/rej.2009.0853.


The purpose was to examine the relationship between performance in the 400-meter walking test and mortality. Data are from a population-based sample of 948 Italian men and women > or =65 years. The main outcome measures that were assessed comprised time to complete the 400-meter walk, 20-meter lap time coefficient of variation, need to rest during the test, and ability to complete the walk. All-cause mortality was ascertained over a 6-year follow-up period. Data were analyzed with proportional hazard logistic and linear regression analyses. In age- and sex-adjusted analyses, all 400-meter walking test variables except need to rest were associated with mortality. After further adjusting for the Mini-Mental State Examination, symptoms of depression, education, smoking, body mass index, being sedentary/minimally active, disease burden, and lower extremity performance (Short Physical Performance Battery score), both time to complete the 400-meter walk and lap time coefficient of variation were significant independent predictors of mortality. We conclude that multiple aspects of performance in the 400-meter walk test provide complementary information on mortality prognosis in older persons.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Activities of Daily Living
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Body Mass Index
  • Exercise
  • Female
  • Geriatric Assessment
  • Health Status
  • Humans
  • Longevity
  • Male
  • Sex Factors
  • Time Factors
  • Walking*