Usefulness of pulse oximetry using the SET technology in critically ill adult patients

Ann Fr Anesth Reanim. 2009 Jul-Aug;28(7-8):640-4. doi: 10.1016/j.annfar.2009.05.017.


Background: Pulse oximeters are routinely used in severely ill patients to detect hypoxemia early. In various clinical situations, however, conventional devices may be unable to display valid values or any value whatsoever. The usefulness of the Signal Extraction Technology (SET) in these situations has not yet been investigated.

Method: Twenty-five adult patients requiring norepinephrine, regardless of the reason or dosage, or having a defective signal with a conventional oximeter were equipped with both their conventional saturation sensor (Oxymax Nellcor) and a SET saturation sensor (Masimo) connected to its monitor. Saturation values displayed by each pulse oximeter and the SaO(2) measured concomitantly by cooximetry were gathered on inclusion and then whenever one of the two sensors did not display a value, or when the difference between the values was greater than five saturation points, or at any time a blood gas analysis was done.

Results: During the study period, 83 measures were collected. Using the Bland and Altman method, SaO(2) estimates by the SET system were more accurate than those by the conventional system (bias+/-2 S.D. of 0.0%+/-3.1% vs 2.1%+/-11.0%, respectively), even when only valid values (values accompanied by a satisfactory quality index) were considered (0.0%+/-2.7% vs 1.2%+/-7.0%).

Conclusions: In situations at risk of producing defective signals when using conventional sensors, the SET system provided more valid SaO(2) estimates.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Critical Illness / therapy*
  • Endpoint Determination
  • Female
  • Humans
  • Male
  • Middle Aged
  • Monitoring, Physiologic
  • Oximetry / methods*
  • Oxygen / blood
  • Signal Processing, Computer-Assisted / instrumentation*


  • Oxygen