Vitiligo update

Semin Cutan Med Surg. 2009 Jun;28(2):86-92. doi: 10.1016/j.sder.2009.04.008.


Vitiligo is an acquired dyschromia of the skin in which there is a loss of epidermal melanocytes. The prevalence of vitiligo is approximately 1% in the United States and 0.1-2% worldwide. The exact pathogenesis of vitiligo remains elusive and is likely multifactorial. After completing this update, participants should be able to discuss the epidemiology of vitiligo and summarize the proposed mechanisms for development of this disease. In addition, they should be able to discuss physical findings, approach to the patient, and some of the therapeutic modalities for this disorder.

Publication types

  • Review

MeSH terms

  • Asian People
  • Black People
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Phototherapy
  • Vitiligo / classification
  • Vitiligo / diagnosis
  • Vitiligo / ethnology*
  • Vitiligo / immunology
  • Vitiligo / physiopathology
  • Vitiligo / therapy*


  • Immunosuppressive Agents