Never forget medication as a cause: vaginal ulceration caused by nicorandil

Am J Obstet Gynecol. 2009 Sep;201(3):e5-6. doi: 10.1016/j.ajog.2009.05.027. Epub 2009 Jul 15.

Abstract

A patient was referred to our vulvar outpatient clinic because of a vaginal ulceration that persisted for 3 years and that had been unresponsive to any prescribed therapy. After a possible association was found with nicorandil therapy, this medication was stopped. Thereafter, the ulceration fully healed within 6 months.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Arrhythmia Agents / adverse effects*
  • Female
  • Humans
  • Nicorandil / adverse effects*
  • Ulcer / chemically induced*
  • Ulcer / pathology
  • Vaginal Diseases / chemically induced*
  • Vaginal Diseases / pathology

Substances

  • Anti-Arrhythmia Agents
  • Nicorandil