Comparison of noninvasive and central arterial blood pressure measurements in ELBW infants

J Perinatol. 2009 Nov;29(11):744-9. doi: 10.1038/jp.2009.86. Epub 2009 Jul 16.


Objective: The objective of this study was to evaluate the difference between noninvasive and central arterial blood pressure measurements in extremely low-birth-weight (ELBW) infants.

Study design: We conducted a retrospective cohort study of infants with birth weight <or=1000 g and who were admitted to a single center in 2005. Paired noninvasive and umbilical arterial blood pressure measurements obtained in the first 72 h were compared. The primary outcome was the differential between the paired measurements. Noninvasive blood pressure (NBP) measurements were defined as clinically acceptable if the differential between the pairs was 15% or lower.

Result: We obtained 146 pairs of measurements from 38 infants. The median absolute differences between noninvasive and arterial systolic, mean and diastolic blood pressure measurements were +18.5, +12 and +10 mm Hg, respectively (percentage differential of 43, 39 and 41%, respectively). In total 75% of the noninvasive measurements of mean blood pressure were clinically unacceptable. No patient or measurement characteristic was significantly associated with clinically unacceptable noninvasive measurements.

Conclusion: In ELBW infants, NBP measurements substantially overestimate systolic, mean and diastolic blood pressures compared with central arterial measurements.

Publication types

  • Comparative Study

MeSH terms

  • Blood Pressure Monitors / statistics & numerical data*
  • Cohort Studies
  • Diastole
  • Equipment Design
  • Female
  • Humans
  • Infant, Extremely Low Birth Weight*
  • Infant, Newborn
  • Intensive Care Units, Neonatal
  • Male
  • Oscillometry / instrumentation
  • Reproducibility of Results
  • Retrospective Studies
  • Systole
  • Transducers, Pressure
  • Umbilical Arteries