Combined Goblet Cell Carcinoid and Mucinous Cystadenoma of the Vermiform Appendix

World J Gastroenterol. 2009 Jul 21;15(27):3431-3. doi: 10.3748/wjg.15.3431.


Goblet cell carcinoid is an uncommon primary tumor of the vermiform appendix, characterized by dual endocrine and glandular differentiation. Whether goblet cell carcinoid represents a morphological variant of appendiceal classical carcinoid or a mucin-producing adenocarcinoma is a matter of conjecture. Rare cases of goblet cell carcinoid with other concomitant appendiceal epithelial neoplasms have been documented. In this report, we describe a rare case of combined appendiceal goblet cell carcinoid and mucinous cystadenoma, and discuss the possible histopathogenesis of this combination.

Publication types

  • Case Reports

MeSH terms

  • Appendiceal Neoplasms / diagnosis
  • Appendiceal Neoplasms / pathology*
  • Appendix / pathology*
  • Biomarkers, Tumor / metabolism
  • Carcinoid Tumor / diagnosis
  • Carcinoid Tumor / pathology*
  • Cystadenoma, Mucinous / diagnosis
  • Cystadenoma, Mucinous / pathology*
  • Female
  • Humans
  • Middle Aged


  • Biomarkers, Tumor