Risk factors, prevention and early detection of prostate cancer

Stacy Loeb; Edward M Schaeffer

doi:10.1016/j.pop.2009.04.007

Risk factors, prevention and early detection of prostate cancer

Prim Care. 2009 Sep;36(3):603-21. doi: 10.1016/j.pop.2009.04.007.

Authors

Stacy Loeb¹, Edward M Schaeffer

Affiliation

¹ Brady Urological Institute, Johns Hopkins Medical Institutions, 600 N Wolfe Street, Marburg 1, Baltimore, MD 21287, USA. stacyloeb@gmail.com

PMID: 19616157
DOI: 10.1016/j.pop.2009.04.007

Abstract

Approximately one in six men in the United States will develop prostate cancer during their lifetime. Genetic and environmental variables play a role in determining prostate cancer risk. This article highlights the latest evidence regarding the risk factors for prostate cancer. The current screening strategies using prostate-specific antigen and digital rectal examination are also discussed, as well as the limitations of these protocols and potential methods for improving early detection.

MeSH terms

Comorbidity
Diet
Dietary Supplements / adverse effects
Environmental Exposure / adverse effects
Genetic Predisposition to Disease
Humans
Male
Mass Screening / methods*
Mass Screening / standards
Practice Guidelines as Topic
Prescription Drugs / adverse effects
Primary Health Care*
Prostate-Specific Antigen / blood
Prostatic Neoplasms / diagnosis*
Prostatic Neoplasms / genetics
Prostatic Neoplasms / prevention & control*
Risk Factors

Substances

Prescription Drugs
Prostate-Specific Antigen