A descriptive review of the factors contributing to nutritional compromise in patients with head and neck cancer

Support Care Cancer. 2009 Nov;17(11):1345-51. doi: 10.1007/s00520-009-0684-5. Epub 2009 Jul 18.

Abstract

Introduction: Malnutrition has been known to be associated with adverse outcomes in cancer patients. Patients who have been and/or are being treated for head and neck cancer have a compromised nutritional status. Nutritional deficits have a significant impact on mortality, morbidity, and quality of life.

Discussion: The wasting in cancer cachexia involves loss of muscle and fat and reflects a catabolic metabolism induced by an abnormal host response to tumor presence and/or tumor factors. Disturbances of various physiological functions like taste, smell, dysphagia, xerostomia apart from cachexia can contribute to long-term nutritional complications and outcome.

Conclusion: Improved management of patients in posttreatment for head and neck cancer may require a multimodal approach by a multidisciplinary team and is best commenced earlier in the trajectory of the disease.

Publication types

  • Review

MeSH terms

  • Cachexia / etiology*
  • Cachexia / physiopathology
  • Deglutition Disorders / etiology*
  • Deglutition Disorders / physiopathology
  • Head and Neck Neoplasms / complications*
  • Head and Neck Neoplasms / radiotherapy
  • Humans
  • Malnutrition / etiology*
  • Malnutrition / physiopathology
  • Nutritional Status / physiology*
  • Quality of Life