Eczema herpeticum and clinical criteria for investigating smallpox

Emerg Infect Dis. 2009 Jul;15(7):1102-4. doi: 10.3201/eid1507.090093.

Abstract

Eczema herpeticum can clinically resemble smallpox. On the basis of the algorithm for rapid evaluation of patients with an acute generalized vesiculopustular rash illness, our patient met criteria for high risk for smallpox. The Tzanck preparation was critical for rapid diagnosis of herpetic infection and exclusion of smallpox.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Animals
  • Antiviral Agents / therapeutic use
  • Dermatitis, Atopic / drug therapy
  • Dermatitis, Atopic / virology*
  • Diagnosis, Differential
  • Herpesvirus 3, Human / isolation & purification
  • Humans
  • Kaposi Varicelliform Eruption / diagnosis*
  • Kaposi Varicelliform Eruption / drug therapy
  • Kaposi Varicelliform Eruption / pathology
  • Male
  • Middle Aged
  • Necrosis
  • Simplexvirus / isolation & purification
  • Smallpox / diagnosis*
  • Smallpox / pathology
  • Treatment Outcome

Substances

  • Antiviral Agents
  • Acyclovir