Endovascular management of adult coarctation and its complications: intermediate results in a cohort of 22 patients

Eur J Cardiothorac Surg. 2010 Feb;37(2):322-7. doi: 10.1016/j.ejcts.2009.04.071. Epub 2009 Jul 26.

Abstract

Objective: To determine the safety and effectiveness of current endovascular treatment in adult patients with thoracic aortic coarctation and its complications.

Methods: A cohort of 22 patients was treated for late presenting primary or recurrent coarctation or aneurysmal formation at varying intervals following childhood intervention.

Results: Ten patients with recently discovered de novo coarctations were treated with balloon-expandable stents, and an endoluminal graft (ELG) was used in one additional patient. In the other 11 patients with recurrent lesions, three underwent repeat balloon dilation and stenting; eight patients with recurrence with aneurysms received ELGs. The gradients across the coarctation decreased from 49 + 16 to 4 + 7 mmHg (p = 0.001), and the diameters increased from 10 + 4 to 19 + 4mm (p = 0.001). In five of the eight patients (63%) with aneurysms, the ELG covered the subclavian artery, and a carotid subclavian bypass was necessary. Two patients required iliac artery access. No early major complications occurred. At mean follow-up of 31 + 15.6 months, one patient with type II leak resolved spontaneously and another developed neck dilation and type I leak, requiring a second ELG placement. All patients except one had improvements in symptoms and better hypertension control.

Conclusions: We conclude that primary or secondary endovascular intervention in adults with de novo or recurrent coarctation and aneurysms is feasible with good intermediate results.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Angioplasty, Balloon / adverse effects
  • Angioplasty, Balloon / methods
  • Aorta, Thoracic / abnormalities*
  • Aortic Aneurysm, Thoracic / surgery
  • Aortic Coarctation / diagnostic imaging
  • Aortic Coarctation / surgery
  • Aortic Coarctation / therapy*
  • Blood Vessel Prosthesis Implantation / methods
  • Epidemiologic Methods
  • Female
  • Humans
  • Male
  • Middle Aged
  • Recurrence
  • Stents
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Young Adult