1H, 13C, and 15N resonance assignments of FK506-binding domain of Plasmodium falciparum FKBP35

Biomol NMR Assign. 2007 Jul;1(1):27-8. doi: 10.1007/s12104-007-9005-4. Epub 2007 May 5.


The immunosuppressant FK506 binds Plasmodium falciparum FK-506 binding protein 35 (PfFKBP35) and shows anti-malarial activity. To understand molecular mechanism of the drug on the parasite, we have done NMR studies. Here, we report the assignment of FK506-binding domain of PfFKBP35.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Binding Sites
  • Nuclear Magnetic Resonance, Biomolecular
  • Plasmodium falciparum / chemistry*
  • Plasmodium falciparum / genetics
  • Protein Structure, Tertiary
  • Protozoan Proteins / chemistry*
  • Protozoan Proteins / genetics
  • Recombinant Proteins / chemistry
  • Recombinant Proteins / genetics
  • Tacrolimus Binding Proteins / chemistry*
  • Tacrolimus Binding Proteins / genetics


  • Protozoan Proteins
  • Recombinant Proteins
  • Tacrolimus Binding Proteins