[Clinical and experimental study of 236 ED nutritional supportive therapy and inosine nutrition protection in postoperative gastric cancer patients]

Zhonghua Zhong Liu Za Zhi. 1990 Nov;12(6):432-4.
[Article in Chinese]


To confirm the effect of nutritional supportive therapy on cancer patients, 52 postoperative gastric cancer patients were selected and given 236 ED as nutritional therapy. Body weight and nutritional index before and after operation, complication, duration in hospital were compared in the experimental group and control. The results showed that there was a significant difference between the two groups. When inosine was given with 236 ED to 30 mice bearing S 180 sarcoma, tumor weight in the treated mice was less than that of the control; level of amino-acids which can stimulate tumor growth decreased whereas c-AMP content in the tumor tissue increased. Based on the above results, a rational nutritional support protocol for tumor patients and a pathomorphological classification of tumor in high, moderate and low nutritional status are proposed.

Publication types

  • English Abstract

MeSH terms

  • Amino Acids / metabolism
  • Animals
  • Cyclic AMP / metabolism
  • Cyclic GMP / metabolism
  • Female
  • Food, Formulated*
  • Humans
  • Inosine / therapeutic use*
  • Male
  • Mice
  • Postoperative Period
  • Prospective Studies
  • Sarcoma 180 / diet therapy
  • Sarcoma 180 / metabolism
  • Stomach Neoplasms / diet therapy*
  • Stomach Neoplasms / metabolism


  • Amino Acids
  • Inosine
  • Cyclic AMP
  • Cyclic GMP