This article discusses the problem of osteoporosis in cerebral palsy. Osteoporosis remains a major health problem worldwide. Cerebral palsy is the most prevalent childhood condition associated with osteoporosis. Bone density is significantly decreased. Children with cerebral palsy often sustain painful fractures with minimal trauma that impair their function and quality of life. This article addresses the anatomy and structure of bone and bone metabolism, the clinical assessment of bone mass, the causes of osteoporosis and its evaluation and treatment in children with cerebral palsy.