Lipotoxicity: why do saturated fatty acids cause and monounsaturates protect against it?

J Gastroenterol Hepatol. 2009 May;24(5):703-6. doi: 10.1111/j.1440-1746.2009.05823.x.
No abstract available

Publication types

  • Comment
  • Editorial

MeSH terms

  • Apoptosis / drug effects*
  • Cytoprotection
  • Fatty Liver / chemically induced*
  • Fatty Liver / genetics
  • Fatty Liver / metabolism
  • Fatty Liver / pathology
  • Fatty Liver / prevention & control
  • Hepatocytes / drug effects*
  • Hepatocytes / metabolism
  • Hepatocytes / pathology
  • Humans
  • Oleic Acid / metabolism
  • Oleic Acid / toxicity*
  • PPAR alpha / metabolism
  • PPAR gamma / metabolism
  • Palmitic Acid / metabolism
  • Palmitic Acid / toxicity*
  • Receptors, G-Protein-Coupled / drug effects
  • Receptors, G-Protein-Coupled / metabolism
  • Signal Transduction / drug effects
  • Triglycerides / metabolism*

Substances

  • PPAR alpha
  • PPAR gamma
  • Receptors, G-Protein-Coupled
  • Triglycerides
  • Oleic Acid
  • Palmitic Acid