Abstract
In Caernorhabditis elegans, homologue pairing is mediated by specialized regions near one end of each chromosome in conjunction with zinc finger (ZnF)-bearing proteins. Families of repeated sequences that are enriched within these regions have now been identified. By recruiting their cognate ZnF-bearing proteins, these regions promote pairing and synapsis.
MeSH terms
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Animals
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Caenorhabditis elegans / genetics*
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Caenorhabditis elegans / metabolism
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Caenorhabditis elegans Proteins / genetics
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Caenorhabditis elegans Proteins / metabolism
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Cell Cycle Proteins / genetics
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Cell Cycle Proteins / metabolism
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Chromosomal Proteins, Non-Histone / genetics
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Chromosomal Proteins, Non-Histone / metabolism
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Chromosome Pairing / genetics*
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Meiosis / genetics*
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Models, Biological
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Synaptonemal Complex / genetics
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Synaptonemal Complex / metabolism
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X Chromosome / genetics*
Substances
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Caenorhabditis elegans Proteins
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Cell Cycle Proteins
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Chromosomal Proteins, Non-Histone
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HIM-8 protein, C elegans
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Zim-1 protein, C elegans
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Zim-2 protein, C elegans
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Zim-3 protein, C elegans