Homologue pairing: getting it right

Nat Cell Biol. 2009 Aug;11(8):917-8. doi: 10.1038/ncb0809-917.

Abstract

In Caernorhabditis elegans, homologue pairing is mediated by specialized regions near one end of each chromosome in conjunction with zinc finger (ZnF)-bearing proteins. Families of repeated sequences that are enriched within these regions have now been identified. By recruiting their cognate ZnF-bearing proteins, these regions promote pairing and synapsis.

Publication types

  • News
  • Comment

MeSH terms

  • Animals
  • Caenorhabditis elegans / genetics*
  • Caenorhabditis elegans / metabolism
  • Caenorhabditis elegans Proteins / genetics
  • Caenorhabditis elegans Proteins / metabolism
  • Cell Cycle Proteins / genetics
  • Cell Cycle Proteins / metabolism
  • Chromosomal Proteins, Non-Histone / genetics
  • Chromosomal Proteins, Non-Histone / metabolism
  • Chromosome Pairing / genetics*
  • Meiosis / genetics*
  • Models, Biological
  • Synaptonemal Complex / genetics
  • Synaptonemal Complex / metabolism
  • X Chromosome / genetics*

Substances

  • Caenorhabditis elegans Proteins
  • Cell Cycle Proteins
  • Chromosomal Proteins, Non-Histone
  • HIM-8 protein, C elegans
  • Zim-1 protein, C elegans
  • Zim-2 protein, C elegans
  • Zim-3 protein, C elegans