The use of sacral neuromodulation for the treatment of non-obstructive urinary retention secondary to Guillain-Barré syndrome

Int Urogynecol J Pelvic Floor Dysfunct. 2009 Sep;20(9):1145-7. doi: 10.1007/s00192-009-0826-9. Epub 2009 Mar 11.


Guillain-Barré syndrome, an acute autoimmune polyneuropathy and demyelinating disease, is characterized by weakness, sensory loss, areflexia, pain, autonomic dysfunction, and occasionally, micturition disturbances including voiding difficulty, urinary retention, nocturnal urinary frequency, and urge incontinence. Typically, urinary dysfunction resolves simultaneously with other neurologic deficits. We report the case of a 20-year-old woman with Guillain-Barré syndrome and persistent urinary retention 18 months following initial diagnosis. This patient is the first described in the literature to undergo successful treatment with sacral neuromodulation. Immediately following neuromodulator placement, the patient voided spontaneously and has had no voiding dysfunction or postvoid residual after 5 months of follow-up.

Publication types

  • Case Reports

MeSH terms

  • Electric Stimulation Therapy*
  • Electrodes, Implanted*
  • Female
  • Guillain-Barre Syndrome / complications*
  • Humans
  • Urinary Bladder, Neurogenic / etiology
  • Urinary Bladder, Neurogenic / therapy
  • Urinary Retention / etiology*
  • Urinary Retention / therapy*
  • Young Adult