Spontaneous cerebral calcific embolus from the aortic arch

Clin Neurol Neurosurg. 2009 Dec;111(10):862-3. doi: 10.1016/j.clineuro.2009.07.006. Epub 2009 Aug 4.


Spontaneous calcific embolism is an uncommon cause of stroke. In most cases calcified cardiac valves are the sources of the emboli although embolization of calcific material from the brachiocephalic trunk has also been described. We report a case of stroke attributable to spontaneous calcific emboli from the aortic arch in which migration of the emboli was observed along the middle cerebral artery following iv tPA.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aorta, Thoracic / pathology*
  • Calculi / drug therapy
  • Calculi / pathology*
  • Echocardiography
  • Embolism / drug therapy
  • Embolism / pathology*
  • Humans
  • Male
  • Middle Cerebral Artery / pathology
  • Plasminogen Activators / therapeutic use
  • Stroke / drug therapy
  • Stroke / etiology
  • Tissue Plasminogen Activator / therapeutic use
  • Tomography, X-Ray Computed


  • Plasminogen Activators
  • Tissue Plasminogen Activator