Determinants of mortality in neonatal intestinal obstruction in Ile Ife, Nigeria

Afr J Paediatr Surg. Jan-Jun 2009;6(1):11-3. doi: 10.4103/0189-6725.48568.

Abstract

Background: Neonatal intestinal obstruction (NIO) is a common cause of mortality. This study determined the causes of mortality in patients with NIO at the Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile Ife.

Patients and methods: Records of all cases of NIO managed at OAUTHC between January 1996 and December 2005 were retrospectively reviewed and the possible factors that may result in mortality were analysed.

Results: Sixty-three neonates with intestinal obstruction were managed, representing 24.3% of the neonatal admissions during the study period. Forty-two were males and 21 were females (M:F = 2:1). The majority (71.4%) of the patients presented within the first week of life. Anorectal malformation constituted 57.1% of the causes of NIO. Other causes included Hirschsprung's disease, duodenal atresia, intestinal malrotation with midgut volvulus and jejunal atresia. There were 18 deaths, with a mortality rate of 28.6%. Reoperation, postoperative bleeding and peroperative sepsis were significant determinants of mortality.

Conclusion: NIO is associated with significant mortality in our centre. Repeat surgery, postoperative bleeding and sepsis were the significant factors that contributed to mortality in NIO.

MeSH terms

  • Abnormalities, Multiple*
  • Female
  • Humans
  • Infant Mortality
  • Infant, Newborn
  • Intestinal Obstruction / complications
  • Intestinal Obstruction / etiology*
  • Intestinal Obstruction / mortality*
  • Male
  • Nigeria / epidemiology
  • Postoperative Hemorrhage
  • Reoperation
  • Retrospective Studies
  • Sepsis