Patient-reported pain and impaired sleep quality in adult patients with cystic fibrosis

J Cyst Fibros. 2009 Sep;8(5):321-5. doi: 10.1016/j.jcf.2009.07.004. Epub 2009 Aug 8.


Background: Sleep impairment has been described in patients with cystic fibrosis (CF). Pain is a known cause of sleep disturbance and as pain is commonly reported in patients with CF, we sought to find an association between impaired sleep quality and pain.

Methods: Fifty adult CF patients completed surveys of pain and sleep quality. The results were analyzed with additional clinical data including age, sex, nutritional status, and lung function.

Results: Thirty-two patients (64%) reported recent pain and 33 patients (66%) reported abnormal sleep quality. The patients with pain report worse sleep quality than those without pain (p=0.006). There was a strong correlation between impaired sleep quality and pain (p<0.0001).

Conclusions: We found that pain and poor sleep quality are reported in a majority of adult CF patients and there is a strong correlation between the two. This will have important clinical implications in the evaluation and treatment of adult patients.

MeSH terms

  • Adolescent
  • Adult
  • Cystic Fibrosis / complications*
  • Female
  • Health Surveys
  • Humans
  • Male
  • Middle Aged
  • Pain / complications
  • Pain / etiology*
  • Sleep Wake Disorders / etiology*
  • Young Adult