Platelet-rich plasma: a literature review

Implant Dent. 2009 Aug;18(4):303-10. doi: 10.1097/ID.0b013e31819e8ec6.


Platelet-rich plasma (PRP) is an autologous concentration of platelets in concentrated plasma, which is extensively used to promote soft and hard tissue healing. The significance behind its use refers to the abundance of growth factors present in a well-prepared PRP concentrate. These growth factors enhance the rate and quality of wound healing by different mechanisms. The objective of this review article is to explain the biological aspect of hard and soft tissue healing by application of PRP in conjunctions with its molecular basis.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Separation
  • Drug Storage
  • Humans
  • Maxillary Sinus / surgery
  • Neovascularization, Physiologic / drug effects
  • Osteogenesis / drug effects
  • Platelet-Derived Growth Factor / pharmacology*
  • Platelet-Rich Plasma*
  • Wound Healing / drug effects*


  • Platelet-Derived Growth Factor