What is the most common phototherapy prescription for psoriasis: NB-UVB or PUVA? Prescription behavior

An Bras Dermatol. 2009 Jul;84(3):244-8. doi: 10.1590/s0365-05962009000300005.
[Article in English, Portuguese]

Abstract

Background: Moderate and severe forms of psoriasis require phototherapy and / or systemic medications. Both UVA and UVB can be used to treat cases of moderate and severe psoriasis, and the effectiveness of both has been proven.

Objective: to access the prescription behavior relating to two types of phototherapy for treating psoriasis refractory to topical treatment: narrowband UVB (NB-UVB) or psoralen plus UVA phototherapy (PUVA).

Methods: Between January 2006 and December 2007, patients referred to two phototherapy services were included in this study. Data on the cases and on the type of prescription were collected retrospectively.

Results: Among the 67 studied patients, 51 (76%) were treated with narrowband UVB. The reasons for the indication were the presence of the guttate type of psoriasis (22%), the presence of thin plaques (15%), the use of drugs that affected photosensitivity (15%), age less than 20 years (9%), skin type I (9%), and liver disease (6%). The remaining 16 (24%) were treated with PUVA. The main indication for this therapy was the severity of the disease (15%), followed by the presence of skin type IV (9%).

Conclusions: Prescriptions of narrowband UVB exceeded those of PUVA because of fewer contraindications and fewer possible side effects, and because it was a more practical option.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Female
  • Humans
  • Male
  • Middle Aged
  • PUVA Therapy / statistics & numerical data
  • Phototherapy / methods*
  • Phototherapy / statistics & numerical data
  • Prescriptions / statistics & numerical data*
  • Psoriasis / therapy*
  • Retrospective Studies
  • Severity of Illness Index
  • Ultraviolet Therapy / statistics & numerical data
  • Young Adult