Structure determination of chamaedryosides A-C, three novel nor-neo-clerodane glucosides from Teucrium chamaedrys, by NMR spectroscopy

Magn Reson Chem. 2009 Nov;47(11):1007-12. doi: 10.1002/mrc.2499.

Abstract

Three new nor-neo-clerodane diterpenes, named chamaedryoside A (1), B (2) and C (3), have been isolated from the organic extracts of Teucrium chamaedrys (L.) and their structural characterization has been accomplished by (1)H and (13)C-NMR spectra, and DEPT, by COSY, TOCSY, HSQC, HSQC-TOSCY and HMBC experiments, as well as by ESI-MS/MS techniques. The stereostructures have been elucidated by NOESY and computational calculations.

MeSH terms

  • Diterpenes, Clerodane / chemistry*
  • Glucosides / chemistry*
  • Magnetic Resonance Spectroscopy / methods*
  • Plant Extracts / chemistry*
  • Teucrium / chemistry*

Substances

  • Diterpenes, Clerodane
  • Glucosides
  • Plant Extracts
  • teucrium extract