Primary synovial sarcoma of kidney: A rare tumor with an atypical presentation

Indian J Urol. 2009 Apr;25(2):269-71. doi: 10.4103/0970-1591.52932.


Synovial sarcoma (SS) is a tumor of the soft tissues with a unique chromosomal translocation t(X;18)(p11.2;q11.2) that can be detected by polymerase chain reaction in tissue homogenates. Here we present a case of a 20-year-old female presenting PSS of the left kidney with caval thrombus. The diagnosis was corroborated by reverse transcription polymerase chain reaction (RT-PCR). Similar cases of PSS of kidney with tumor extension in the inferior vena cava are extremely rare and to date, approximately three cases have been reported in the literature.

Keywords: Renal cell carcinoma; chromosomal translocation; synovial sarcoma.