Intraocular pressure change in orbital disease

Surv Ophthalmol. Sep-Oct 2009;54(5):519-44. doi: 10.1016/j.survophthal.2009.02.023.


Intraocular pressure change has been found concurrent with many orbital pathologies, particularly those involving proptosis. The objective of this review is to offer an inclusive classification of orbital disease-related intraocular pressure change, not only for oculoplastics and glaucoma specialists, but also for general ophthalmologists. Various orbital conditions associated with increased intraocular pressure and glaucoma are comprehensively summarized, and pathophysiology, clinical manifestations, and treatment options of these diseases are discussed. Graves disease, arterio-venous shunts, trauma, and orbital neoplasia, and other common conditions are discussed in detail; less frequent syndromes such as orbitocraniofacial deformities, phakomatoses, and mucopolysaccharidoses are included for the sake of comprehensiveness, but discussed less extensively.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Glaucoma / physiopathology
  • Humans
  • Intraocular Pressure / physiology*
  • Ocular Hypertension / diagnosis
  • Ocular Hypertension / physiopathology*
  • Ocular Hypertension / therapy
  • Orbital Diseases / diagnosis
  • Orbital Diseases / physiopathology*
  • Orbital Diseases / therapy