Can the protein occupancy landscape show the topologically isolated chromosomal domains in the E. coli genome?: An exciting prospect

Byung-Kwan Cho; Bernhard Ø Palsson

doi:10.1016/j.molcel.2009.07.019

Can the protein occupancy landscape show the topologically isolated chromosomal domains in the E. coli genome?: An exciting prospect

Mol Cell. 2009 Aug 14;35(3):255-6. doi: 10.1016/j.molcel.2009.07.019.

Authors

Byung-Kwan Cho¹, Bernhard Ø Palsson

Affiliation

¹ Department of Bioengineering, University of California, San Diego, La Jolla, 92093, USA.

PMID: 19683488
DOI: 10.1016/j.molcel.2009.07.019

Abstract

In a recent issue of Molecular Cell, Vora et al. (2009) introduce an in vivo protein occupancy display (IPOD) technology and propose that the domains extensively occupied by proteins with inactive transcription in bacteria are mainly topologically isolated chromosomal domains.

Publication types

Comment

MeSH terms

Binding Sites
Chromatin Immunoprecipitation
Chromosomes, Bacterial / chemistry
Chromosomes, Bacterial / metabolism*
DNA Footprinting
Escherichia coli / genetics*
Escherichia coli / metabolism
Escherichia coli Proteins / genetics
Escherichia coli Proteins / metabolism*
Genome, Bacterial*

Substances

Escherichia coli Proteins