Cytological analysis of meiosis in Caenorhabditis elegans

Methods Mol Biol. 2009;558:171-95. doi: 10.1007/978-1-60761-103-5_11.


The nematode Caenorhabditis elegans has emerged as an informative experimental system for analysis of meiosis, in large part because of the advantageous physical organization of meiotic nuclei as a gradient of stages within the germline. Here we provide tools for detailed observational studies of cells within the worm gonad, including techniques for light and electron microscopy.

Publication types

  • Review

MeSH terms

  • Animals
  • Caenorhabditis elegans / cytology*
  • Caenorhabditis elegans / genetics*
  • Cytological Techniques / methods*
  • Meiosis / genetics
  • Meiosis / physiology*
  • Microscopy, Electron / methods
  • Models, Biological