Imaging of the pancreas with secretin enhancement

Top Magn Reson Imaging. 2009 Feb;20(1):19-24. doi: 10.1097/RMR.0b013e3181b483f0.


Magnetic resonance cholangiopancreatography is a noninvasive imaging technique for evaluation of the pancreatic duct and the biliary tree. Secretin is a polypeptide hormone that has numerous physiological effects, including stimulation of the pancreatic secretion of bicarbonate-rich fluid and transient increase in the tone in the sphincter of Oddi. As a result, secretin administration usually results in distention of the pancreatic duct; therefore, visualization of the pancreatic ductal anatomy is often substantially improved. Awareness of its value by referring clinicians and radiologists will increase its use in the future.

Publication types

  • Review

MeSH terms

  • Cholangiopancreatography, Magnetic Resonance / methods*
  • Cholangiopancreatography, Magnetic Resonance / trends*
  • Contrast Media
  • Humans
  • Pancreas / pathology*
  • Pancreatic Diseases / diagnosis*
  • Secretin*


  • Contrast Media
  • Secretin