Catalytic direct acetoxylation of indoles

Ilga Mutule; Edgars Suna; Kristofer Olofsson; Benjamin Pelcman

doi:10.1021/jo901321b

Catalytic direct acetoxylation of indoles

J Org Chem. 2009 Sep 18;74(18):7195-8. doi: 10.1021/jo901321b.

Authors

Ilga Mutule¹, Edgars Suna, Kristofer Olofsson, Benjamin Pelcman

Affiliation

¹ Latvian Institute of Organic Synthesis, Aizkraukles 21, LV-1006, Riga, Latvia.

PMID: 19689144
DOI: 10.1021/jo901321b

Abstract

3-Acetoxyindole-2-carboxylates could be readily synthesized in a Pd(OAc)(2)- or PtCl(2)-catalyzed direct C-3 acetoxylation of indole-2-carboxylates using PhI(OAc)(2) as a terminal oxidant.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetylation
Carboxylic Acids / chemistry
Catalysis
Indoles / chemical synthesis*
Indoles / chemistry
Models, Chemical
Oxidants / chemistry
Palladium / chemistry*

Substances

Carboxylic Acids
Indoles
Oxidants
indole-2-carboxylate
Palladium