Fine needle aspiration of male breast lesions

Acta Cytol. Jul-Aug 2009;53(4):369-74. doi: 10.1159/000325335.

Abstract

Objective: To describe a biinstitutional experience with fine needle aspiration (FNA) of breast lesions occurring in men over a period of over 10 years and to assess the role of FNA in detecting male breast cancer.

Study design: Computer patient records were searched from January 1990 to September 2007. Male patients who had a diagnosis of carcinoma on breast biopsy or resection were identified, and detailed chart review was done to assess demographics and correlate biopsy and FNA results.

Results: A total of 346, 792 patients' charts were searched, and 217 male patients were found to have had a breast mass and subsequent FNA. Combined in both institutions, FNA results were positive for carcinoma in 12 (5.5%) cases, negative in 181 (83.4%) cases, suspicious in 5 (2.3%) cases, indeterminate/inconclusive in 3 (1.4%) cases and unsatisfactory in 16 (7.4%) cases. Matching biopsies to confirm FNA results were available in 26 (12%) of the 217 cases. The calculated sensitivity and specificity for the malignant cases reached 100%. When suspicious cases were calculated for diagnostic accuracy, the sensitivity was 67% and the specificity 100%.

Conclusion: This biinstitutional study demonstrates that FNA is a reliable but underutilized procedure for the management of male breast lesions.

Publication types

  • Evaluation Study
  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Biopsy
  • Biopsy, Fine-Needle* / methods
  • Breast / pathology
  • Breast Neoplasms, Male / pathology*
  • Carcinoma / pathology*
  • Humans
  • Male
  • Middle Aged
  • Sensitivity and Specificity