[The evaluation of Identifiler system in paternity testing]

Fa Yi Xue Za Zhi. 2009 Jun;25(3):184-6.
[Article in Chinese]

Abstract

Objective: To evaluate the power of Identifiler System for paternity testing.

Methods: A total of 3 277 paternity testing cases were studied using Identifiler System. The exclusion power and mutation rates of the Identifiler System were analysed in the paternity testing.

Results: The cumulated power of exclusion was 0.999 998 827, and the cumulated discriminating power was 0.999 999 999 999 999 98, respectively. Of the 3 277 cases, paternity was confirmed in 2 863, but excluded in 347. Among this paternity testing, mutations involving a single STR locus were observed in 65 cases, while mutations involving 2 STR loci were observed in 2 cases.

Conclusion: The Identifiler System is powerful and reliable for paternity testing.

Publication types

  • Evaluation Study

MeSH terms

  • Alleles
  • China
  • DNA Fingerprinting / methods*
  • Forensic Genetics / methods*
  • Genetic Testing / methods
  • Genetics, Population*
  • Humans
  • Microsatellite Repeats
  • Mutation*
  • Paternity*
  • Polymerase Chain Reaction / methods
  • Probability
  • Tandem Repeat Sequences / genetics*