Subcutaneous infusions for control of cancer symptoms

J Pain Symptom Manage. 1990 Feb;5(1):33-41. doi: 10.1016/s0885-3924(05)80007-7.

Abstract

Continuous subcutaneous infusions offer a safe, simple, effective alternative to intravenous or intramuscular injections when oral medications cannot be used. They are extremely useful for cancer patients suffering from pain, vomiting, seizures, and other symptoms. Hydromorphone or morphine may be combined with metoclopramide, methotrimeprazine, or haloperidol (in D5W only), in the same pump to control both pain and nausea. Seizures can be controlled by subcutaneous infusion of phenobarbital or midazolam. If proper doses are prescribed and skin irritation is watched for, they can be used safely in the patient's home.

MeSH terms

  • Analgesics / administration & dosage*
  • Analgesics, Opioid / administration & dosage*
  • Humans
  • Infusions, Parenteral / methods
  • Nausea / drug therapy
  • Neoplasms / physiopathology*
  • Pain, Intractable / drug therapy*
  • Vomiting / drug therapy

Substances

  • Analgesics
  • Analgesics, Opioid