Vitamin D: bone and beyond, rationale and recommendations for supplementation

Am J Med. 2009 Sep;122(9):793-802. doi: 10.1016/j.amjmed.2009.02.029.

Abstract

Adequate vitamin D status is necessary and beneficial for health, although deficiency plagues much of the world's population. In addition to reducing the risk for bone disease, vitamin D plays a role in reduction of falls, as well as decreases in pain, autoimmune diseases, cancer, heart disease, mortality, and cognitive function. On the basis of this emerging understanding, improving patients' vitamin D status has become an essential aspect of primary care. Although some have suggested increased sun exposure to increase serum vitamin D levels, this has the potential to induce photoaging and skin cancer, especially in patients at risk for these conditions. Vitamin D deficiency and insufficiency can be both corrected and prevented safely through supplementation.

Publication types

  • Review

MeSH terms

  • Bone Density Conservation Agents / therapeutic use*
  • Dietary Supplements*
  • Humans
  • Vitamin D / physiology
  • Vitamin D / therapeutic use*
  • Vitamin D Deficiency / complications
  • Vitamin D Deficiency / drug therapy*
  • Vitamin D Deficiency / epidemiology

Substances

  • Bone Density Conservation Agents
  • Vitamin D