Methods for evaluation of platelet function

Transfus Apher Sci. 2009 Oct;41(2):121-5. doi: 10.1016/j.transci.2009.07.015. Epub 2009 Aug 21.


There are a multitude of platelet function tests available, reflecting the complex nature of the platelet in haemostasis. No simple single test will ever cover all aspects of platelet function. Some tests focus on the aggregation of platelets, for example aggregometry, other on the swelling in response to hypotonic solutions, i.e. the well-known hypotonic shock response, or adhesion or coagulation and clot retraction, for example thromboelastography. In general there is a lack of clinical studies showing a predictive value of analysis of platelet concentrates.

MeSH terms

  • Bleeding Time
  • Blood Platelets / physiology*
  • Flow Cytometry
  • Humans
  • Platelet Function Tests / methods*