Susceptibility to infectious diseases based on antimicrobial peptide production

Infect Immun. 2009 Nov;77(11):4690-5. doi: 10.1128/IAI.01515-08. Epub 2009 Aug 24.


In the last few years, the great impact of antimicrobial peptides on infectious disease susceptibility and natural resistance has been reported. In some cases, susceptibility to diseases is related to antimicrobial peptide polymorphisms and gene copy numbers, but for the vast majority of infectious diseases, these phenomena need to be elucidated. This review is focused on the current knowledge about susceptibility and resistance conferred by genetic variations in antimicrobial peptide expression in infectious diseases.

Publication types

  • Review

MeSH terms

  • Animals
  • Antimicrobial Cationic Peptides / genetics*
  • Antimicrobial Cationic Peptides / immunology*
  • Communicable Diseases / genetics*
  • Communicable Diseases / immunology*
  • Genetic Predisposition to Disease*
  • Humans


  • Antimicrobial Cationic Peptides