Successful management of Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon using vincristine and ticlopidine

Pediatr Dermatol. 2009 May-Jun;26(3):365-6. doi: 10.1111/j.1525-1470.2009.00923.x.

Abstract

Kaposiform hemangioendothelioma is a rare locally aggressive vascular tumor that usually occurs in skin and retroperitoneum of infants and young children. We present a case of a newborn with a rapid tumor growth and a life-threatening Kasabach-Merritt syndrome with a progressive remission after treatment with vincristine and ticlopidine.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents, Phytogenic / administration & dosage*
  • Blood Coagulation Disorders / complications*
  • Blood Coagulation Disorders / drug therapy
  • Fibrinolytic Agents / administration & dosage*
  • Hemangioendothelioma / complications
  • Hemangioendothelioma / drug therapy*
  • Humans
  • Infant
  • Male
  • Skin Neoplasms / complications
  • Skin Neoplasms / drug therapy*
  • Ticlopidine / administration & dosage*
  • Vincristine / administration & dosage*

Substances

  • Antineoplastic Agents, Phytogenic
  • Fibrinolytic Agents
  • Vincristine
  • Ticlopidine