Scalp acupuncture (SA) is a modality based on different physiologic functions of different brain areas, using needles to stimulate different scalp zones so as to excite the reflex-related nervous tissue. The findings of several studies showed that the clinical effect of SA on stroke was significant, but the exact mechanism is still unclear. In this research, some new ways of thinking and new methodological standards on stroke experiment using SA are put forward. They are as follows: A, establishment of standard animal model of stroke; B, simulation of head acupoint line on animal model following traditional Chinese medicine localization; C, acupuncture manipulation and quantity of stimulus for SA in animal model; D, optimal curative opportunity and instant effect of SA therapy on stroke; E, mechanism study of SA on stroke. This research may provide methodological reference for future mechanism study on stroke experiment using SA.