Association between Graves' ophthalmopathy and smoking

Lancet. 1990 May 26;335(8700):1261-3. doi: 10.1016/0140-6736(90)91315-2.


Patients with Graves' disease were questioned by postal survey about their smoking history. There were significantly more smokers in the group with ophthalmopathy than in the group with Graves' thyrotoxicosis or controls. Patients with severe eye signs smoked significantly more tobacco than did those with less serious signs.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Evaluation Studies as Topic
  • Graves Disease / etiology*
  • Graves Disease / therapy
  • Humans
  • Middle Aged
  • Sampling Studies
  • Severity of Illness Index
  • Smoking / adverse effects*
  • Surveys and Questionnaires
  • Thyrotoxicosis / etiology*