A role for the ribosome in development

Trends Plant Sci. 2009 Sep;14(9):512-9. doi: 10.1016/j.tplants.2009.06.009. Epub 2009 Aug 27.


Development of a multicellular organism involves coordinated cell division, growth and specialization to generate different cell types that contribute to organized tissues, distinct organs and a higher order body plan. This coordinated process requires tight regulation of gene expression, which is mediated by multiple transcriptional, post-transcriptional, translational and post-translational control mechanisms. As I discuss here, recent studies on ribosomal protein genes and ribosome assembly genes indicate that the basic translational machinery of the cell, the ribosome, has a regulatory role in plant development. A comparison between plants and animals reveals both divergent trends in the genome content of ribosomal proteins and intriguing potential overlaps in the role of the ribosome in development.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Arabidopsis / genetics
  • Arabidopsis / growth & development*
  • Arabidopsis / metabolism*
  • Eukaryotic Cells / metabolism
  • Mutation / genetics
  • Phenotype
  • Ribosomal Proteins / genetics
  • Ribosomal Proteins / metabolism
  • Ribosomes / metabolism*


  • Ribosomal Proteins