Human-specific evolution of sialic acid targets: explaining the malignant malaria mystery?

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14739-40. doi: 10.1073/pnas.0908196106. Epub 2009 Aug 26.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Biological Evolution*
  • Host-Parasite Interactions
  • Humans
  • Malaria / parasitology*
  • Malaria / transmission
  • Malaria / veterinary
  • Membrane Glycoproteins / genetics
  • N-Acetylneuraminic Acid / metabolism
  • Pan troglodytes
  • Plasmodium / chemistry
  • Plasmodium / genetics*
  • Plasmodium / metabolism
  • Plasmodium falciparum / chemistry
  • Plasmodium falciparum / genetics*
  • Plasmodium falciparum / metabolism
  • Protozoan Infections, Animal / parasitology
  • Protozoan Proteins / chemistry
  • Protozoan Proteins / metabolism

Substances

  • Membrane Glycoproteins
  • Protozoan Proteins
  • circumsporozoite protein, Protozoan
  • N-Acetylneuraminic Acid