ANCHOR: web server for predicting protein binding regions in disordered proteins

Bioinformatics. 2009 Oct 15;25(20):2745-6. doi: 10.1093/bioinformatics/btp518. Epub 2009 Aug 28.

Abstract

ANCHOR is a web-based implementation of an original method that takes a single amino acid sequence as an input and predicts protein binding regions that are disordered in isolation but can undergo disorder-to-order transition upon binding. The server incorporates the result of a general disorder prediction method, IUPred and can carry out simple motif searches as well.

Availability: The web server is available at http://anchor.enzim.hu. The program package is freely available for academic users.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Binding Sites
  • Computational Biology / methods*
  • Databases, Protein
  • Internet*
  • Protein Conformation
  • Proteins / chemistry*
  • Proteins / metabolism
  • Sequence Analysis, Protein
  • Software*

Substances

  • Proteins