Despite the relatively high prevalence of coronary artery disease in women, there are little data on the investigation and treatment of ischemic heart disease in this population. In the last couple of decades authors have addressed health problems in minorities, including women. The great majority of these studies included the acute coronary syndrome population but most recent ones have focused on the management of stable angina from a gender perspective. Many of those studies showed that there are inequities between genders regarding the care of patients with ischemic heart disease. Although little is known about the prognostic implications of such differences, studies have shown that suboptimal treatment in women leads to poor clinical outcomes. Gender-specific and both epidemiological and pathophysiological data are needed.