Human cytomegalovirus: purification of enveloped virions and dense bodies

J Gen Virol. 1977 Aug;36(2):345-9. doi: 10.1099/0022-1317-36-2-345.


Enveloped virions and dense bodies of human cytomegalovirus have been purified by centrifugation, using combination negative viscosity: positive density gradients. Light-scattering bands of each component were obtained, and when these were examined by immune electron microscopy minimal cross contamination was observed.

MeSH terms

  • Cell Line
  • Centrifugation, Density Gradient
  • Cytomegalovirus / isolation & purification*
  • Cytomegalovirus / ultrastructure
  • Humans
  • Inclusion Bodies, Viral*