[Foods rich in fat-soluble vitamins and bone health]

Clin Calcium. 2009 Sep;19(9):1362-9.
[Article in Japanese]


Intervention studies and meta-analyses have shown that vitamin D(3) at 700-800 IU/day decreases the fracture incidence. Higher phylloquinone (vitamin K(1)) intake or "natto" intake was associated with lower fracture incidence. In contrast, current intake of vitamin D and K in Japanese is likely to be unsatisfactory for preventing fracture. The intake of fish, abundant in vitamin D(3) is encouraged. Regarding vitamin K, "natto" intake is strongly recommended, since it contains extraordinary amount of menaquinone-7. Phylloquinone in green vegetables would be efficiently absorbed when cooked with oil. Thus Japanese traditional foods seem to be appropriate for bone health.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Cholecalciferol / administration & dosage*
  • Dietary Fats
  • Female
  • Food Analysis*
  • Fractures, Bone / prevention & control*
  • Humans
  • Male
  • Risk
  • Solubility
  • Soy Foods
  • Vitamin K 1 / administration & dosage*
  • Vitamin K 2 / analogs & derivatives


  • Dietary Fats
  • Vitamin K 2
  • Cholecalciferol
  • Vitamin K 1
  • vitamin MK 7