Overcorrection of hyponatremia is a medical emergency

Kidney Int. 2009 Sep;76(6):587-9. doi: 10.1038/ki.2009.251.


Overcorrection of hyponatremia is a medical emergency. Excessive correction usually results from the unexpected emergence of a water diuresis after resolution of the cause of water retention. The concurrent administration of desmopressin and 5% dextrose in water can be given to cautiously re-lower the serum sodium concentration when therapeutic limits have been exceeded. Nephrologists should be equally aggressive in correcting hyponatremia and in un-correcting it when their patients get too much of a good thing.

Publication types

  • Comment
  • Letter

MeSH terms

  • Carbon Dioxide / blood
  • Demyelinating Diseases / etiology
  • Emergencies
  • Humans
  • Hyponatremia / therapy*
  • Myelinolysis, Central Pontine / etiology
  • Oxygen / blood
  • Sodium / blood


  • Carbon Dioxide
  • Sodium
  • Oxygen