Prevalence of epilepsy and seizure disorders as causes of apparent life- threatening event (ALTE) in children admitted to a tertiary hospital

Arq Neuropsiquiatr. 2009 Sep;67(3A):616-20. doi: 10.1590/s0004-282x2009000400008.

Abstract

Objective: To determine the prevalence and describe clinical characteristics of seizure disorders and epilepsy as causes of apparent life- threatening event (ALTE) in children admitted at the emergency and followed in a tertiary hospital.

Method: Cross-sectional study with prospective data collection using specific guidelines to determine the etiology of ALTE.

Results: During the study, 30 (4.2%) children admitted to the hospital had a diagnosis of ALTE. There was a predominance of males (73%) and term infants (70%). Neonatal neurological disorders and neuropsychomotor development delay were found respectively in 13.4% and 10% of the cases. Etiological investigation revealed that 50% of the cases were idiopathic, and 13.4% were caused by epilepsy or seizure disorders. Although all patients had recurrent ALTE events, epilepsy had not been previously suspected.

Conclusion: Epilepsy should be included in the differential diagnosis of ALTE, particularly when events are recurrent.

Publication types

  • Case Reports

MeSH terms

  • Anticonvulsants / therapeutic use
  • Carbamazepine / therapeutic use
  • Cross-Sectional Studies
  • Emergency Service, Hospital / statistics & numerical data
  • Epilepsy / diagnosis
  • Epilepsy / drug therapy
  • Epilepsy / epidemiology*
  • Female
  • Fructose / analogs & derivatives
  • Fructose / therapeutic use
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Prevalence
  • Prospective Studies
  • Recurrence
  • Topiramate

Substances

  • Anticonvulsants
  • Topiramate
  • Fructose
  • Carbamazepine