Laser corneal biofilm disruption for infectious crystalline keratopathy

Clin Exp Ophthalmol. 2009 Mar;37(2):177-80. doi: 10.1111/j.1442-9071.2008.01912.x. Epub 2008 Dec 29.


Crystalline keratopathy can be successfully treated by the Nd:YAG laser. We present two cases of crystalline keratopathy managed this way. A 36-year-old female contact lens wearer presented with crystalline keratopathy following recent treatment with topical steroids and antibiotics for a corneal abscess. In this case crystalline keratopathy developed despite the intensive topical antibiotic treatment. A 55-year-old man with a history of acne rosacea, chronic myelomonocytic leukaemia, asthma and Crohn's disease presented with crystalline keratopathy following an episode of infectious keratitis. Treatment with the Nd:YAG laser to the area of involvement was instituted in both cases. Noticeable resolution occurred within days, with subsequent full recovery. No side-effects from the use of the Nd:YAG laser were noted. There have been only two cases previously reported using this treatment modality.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biofilms*
  • Corneal Diseases / microbiology
  • Corneal Diseases / pathology
  • Corneal Diseases / surgery*
  • Corneal Stroma / microbiology
  • Corneal Stroma / surgery
  • Eye Infections, Bacterial / microbiology
  • Eye Infections, Bacterial / pathology
  • Eye Infections, Bacterial / surgery*
  • Female
  • Humans
  • Laser Therapy*
  • Lasers, Solid-State / therapeutic use*
  • Male
  • Middle Aged
  • Staphylococcal Infections / microbiology
  • Staphylococcal Infections / pathology
  • Staphylococcal Infections / surgery*