Nitrofurantoin-induced systemic inflammatory response syndrome

Am J Med Sci. 2009 Oct;338(4):338-40. doi: 10.1097/MAJ.0b013e3181abd9f6.

Abstract

Nitrofurantoin is a commonly used antibiotic for the prophylaxis and treatment of urinary tract infections. We report the first case of nitrofurantoin-induced systemic inflammatory response syndrome, an important adverse drug reaction in the setting of what was initially believed to be a recurrent infection.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Escherichia coli Infections / complications
  • Escherichia coli Infections / drug therapy
  • Gram-Negative Bacterial Infections / drug therapy*
  • Gram-Negative Bacterial Infections / microbiology
  • Humans
  • Male
  • Nitrofurantoin / adverse effects*
  • Nitrofurantoin / therapeutic use
  • Stenotrophomonas / isolation & purification*
  • Systemic Inflammatory Response Syndrome / chemically induced*
  • Systemic Inflammatory Response Syndrome / complications
  • Urinary Bladder Neoplasms / complications
  • Urinary Bladder Neoplasms / drug therapy

Substances

  • Nitrofurantoin