Serum vitamin A and beta-carotene levels in children with asthma

J Asthma. 2009 Sep;46(7):699-702. doi: 10.1080/02770900903056195.


Background: Low serum levels of dietary antioxidants are associated with allergic diseases including asthma. Vitamin A and carotenoids are dietary antioxidants that are likely to play an important role against airway inflammation.

Methods: This study included 433 asthmatic schoolchildren and 537 healthy control subjects, between 6 and 18 years of age. Serum beta-carotene, vitamin A, cholesterol, and triglycerides levels were studied in all subjects.

Results: Serum vitamin A concentration was significantly lower in asthmatic subjects than in healthy control subjects (19.4 +/- 1.1 mg/dL vs. 28.9 +/- 0.86 mg/dL) (p < 0.001). There were no significant differences in the levels of beta-carotene, cholesterol, and triglycerides between the two groups.

Conclusion: Reduction of vitamin A in asthmatic children may have etiological implications for the disease.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Aging / blood
  • Asthma / blood*
  • Child
  • Cholesterol / blood
  • Female
  • Humans
  • Male
  • Saudi Arabia
  • Sex Factors
  • Triglycerides / blood
  • Vitamin A / blood*
  • Vitamin A Deficiency / blood
  • beta Carotene / blood*


  • Triglycerides
  • beta Carotene
  • Vitamin A
  • Cholesterol