Virucidal activity of disinfectants: studies with the poliovirus

J Hosp Infect. 1990 May;15(4):339-45. doi: 10.1016/0195-6701(90)90090-b.


The activity of various disinfectants against poliovirus (Sabin 1 an) was assessed using surface and suspension tests. The surface test showed that 2% glutaraldehyde and high concentrations of hypochlorites (9200 ppm avCl2) were effective (i.e. greater than or equal to 4 log10 reduction) against a dried virus suspension in 1 min. Diluted aldehydes ('Sporicidin' and 'Gigasept'), lower hypochlorite concentrations (1000 ppm avCl2) and peroxides (3%) were less effective while 70% ethanol showed variable results; 70% isopropanol was ineffective in 10 min. In the suspension tests hydrogen peroxide (3% and 6%) and 70% ethanol were ineffective in 1 min.

Publication types

  • Comparative Study

MeSH terms

  • Disinfectants / pharmacology*
  • Microbial Sensitivity Tests
  • Poliovirus / drug effects*
  • Poliovirus / growth & development


  • Disinfectants